A/Prof Maia Lesosky

Maia Lesosky

Associate Professor Maia Lesosky

Dept. of Public Health & Family Medicine
TitleAssociate Professor
NameMaia Lesosky
Work Telephone021 650 4532
Primary Email
DepartmentDept. of Public Health & Family Medicine
Other AffiliationsCIDER

Decloedt, E. H., Lesosky, M. R., Maartens, G., & Joska, J. A. (2017). Renal safety of lithium in HIV-infected patients established on tenofovir disoproxil fumarate containing antiretroviral therapy: analysis from a randomized placebo-controlled trial. AIDS Research and Therapy, 14, 6. doi:10.1186/s12981-017-0134-2. Full text: http://dx.doi.org/10.1186/s12981-017-0134-2

Dheda, K., Limberis, J. D., Pietersen, E., Phelan, J., Esmail, A., Lesosky, M. R., Fennelly, K. P., te Riele, J., Mastrapa, B., Streicher, E. M., Dolby, T., Abdallah, A. M., Ben-Rached, F., Simpson, J., Smith, L., Gumbo, T., van Helden, P., Sirgel, F. A., McNerney, R., Theron, G., Pain, A., Clark, T. G., & Warren, R. M. (2017). Outcomes, infectiousness, and transmission dynamics of patients with extensively drug-resistant tuberculosis and home-discharged patients with programmatically incurable tuberculosis: a prospective cohort study. The Lancet Respiratory Medicine, 5, 269-281. doi:10.1016/S2213-2600(16)30433-7. Full text: http://dx.doi.org/10.1016/S2213-2600(16)30433-7

Meiring, T. L., Mbulawa, Z. Z. A., Lesosky, M. R., Coetzee, D. J., & Williamson, A. (2017). High diversity of alpha, beta and gamma human papillomaviruses in genital samples from HIV-negative and HIV-positive heterosexual South African men. Papillomavirus Research, 3, 160-167.

Myer, B. L., Dunning, L., Lesosky, M. R., Hsiao, N., Phillips, T., Petro, G., Zerbe, A., McIntyre, J. A., & Abrams, E. J. (2017). Frequency of Viremic Episodes in HIV-Infected Women Initiating Antiretroviral Therapy During Pregnancy: A Cohort Study. Clinical Infectious Diseases, 64, 422-427. doi:10.1093/cid/ciw792. Full text: http://dx.doi.org/10.1093/cid/ciw792

Rockwood, N., Pasipanodya, J. G., Denti, P., Sirgel, F., Lesosky, M. R., Gumbo, T., Meintjes, G., McIlleron, H., & Wilkinson, R. J. (2017). Concentration-Dependent Antagonism and Culture Conversion in Pulmonary Tuberculosis. Clinical Infectious Diseases, 64, 1350-1359. doi:10.1093/cid/cix158. Full text: http://dx.doi.org/10.1093/cid/cix158

Bana, T. M., Lesosky, M. R., Pepper, D. J., van der Plas, H., Schutz, C., Goliath, R., Morroni, C., Mendelson, M., Maartens, G., Wilkinson, R. J., & Meintjes, G. (2016). Prolonged tuberculosis-associated immune reconstitution inflammatory syndrome: characteristics and risk factors. BMC Infectious Diseases, 16, 518. doi:10.1186/s12879-016-1850-2. Full text: http://dx.doi.org/10.1186/s12879-016-1850-2

Decloedt, E. H., Freeman, C., Howells, F., Casson-Crook, M., Lesosky, M. R., Koutsilieri, E., Lovestone, S., Maartens, G., & Joska, J. A. (2016). Moderate to severe HIV-associated neurocognitive impairment: A randomized placebo-controlled trial of lithium. Medicine (Baltimore), 95, e5401. doi:10.1097/md.0000000000005401. Full text: http://dx.doi.org/10.1097/md.0000000000005401

Esmail, H., Lai, R. P., Lesosky, M. R., Wilkinson, K. A., Graham, C. M., Coussens, A. K., Oni, T., Warwick, J. M., Said-Hartley, Q., Koegelenberg, C. F., Walzl, G., Flynn, J. L., Young, D. B., Barry Iii, C. E., O'Garra, A., & Wilkinson, R. J. (2016). Characterization of progressive HIV-associated tuberculosis using 2-deoxy-2-<18F>fluoro-D-glucose positron emission and computed tomography. Nature Medicine, 22, 1090-1093. doi:10.1038/nm.4161. Full text: http://dx.doi.org/10.1038/nm.4161

Grigg, J., Whitehouse, A., Pandya, H., Turner, S., Griffiths, C. J., Vulliamy, T., T. Walton, R., Price, D. B., Sanak, M., Holloway, J. W., Noimark, L., Lesosky, M. R., Brugha, R., Koh, L., & Nwokoro, C. (2016). Urinary prostanoids in preschool wheeze. European Respiratory Journal, 49(5). doi:10.1183/13993003.01390-2016. Full text: http://dx.doi.org/10.1183/13993003.01390-2016

Grimsrud, A. T., Lesosky, M. R., Kalombo, C., Bekker, L., & Myer, B. L. (2016). Implementation and operational research: community-based adherence clubs for the management of stable antiretroviral therapy patients in Cape Town, South Africa: a cohort study. JAIDS Journal of Acquired Immune Deficiency Syndromes, 71, e16-e23.

Marais, S., Meintjes, G., Lesosky, M. R., Wilkinson, K. A., & Wilkinson, R. J. (2016). Interleukin-17 mediated differences in the pathogenesis of HIV-1-associated tuberculous and cryptococcal meningitis. AIDS, 30, 395-404. doi:10.1097/qad.0000000000000904. Full text: http://dx.doi.org/10.1097/qad.0000000000000904

Myer, B. L., Dunning, L., Lesosky, M. R., Hsiao, N., Phillips, T., Petro, G., Zerbe, A., McIntyre, J. A., & Abrams, E. J. (2016). Frequency of viremic episodes in HIV-infected women initiating antiretroviral therapy during pregnancy: a cohort study. Clinical Infectious Diseases, 64, ciw792.

Peter, J. G., Zijenah, L. S., Chanda, D., Clowes, P., Lesosky, M. R., Gina, P., Mehta, N., Calligaro, G., Lombard, C. J., Kadzirange, G., Bandason, T., Chansa, A., Liusha, N., Mangu, C., Mtafya, B., Msila, H., Rachow, A., Hoelscher, M., Mwaba, P., Theron, G., & Dheda, K. (2016). Effect on mortality of point-of-care, urine-based lipoarabinomannan testing to guide tuberculosis treatment initiation in HIV-positive hospital inpatients: a pragmatic, parallel-group, multicountry, open-label, randomised controlled trial. The Lancet, 387, 1187-1197. doi:10.1016/S0140-6736(15)01092-2. Full text: http://dx.doi.org/10.1016/S0140-6736(15)01092-2

Calligaro, G. L., Theron, G., Khalfey, H., Peter, J., Meldau, R., Matinyenya, B., Davids, M., Smith, L., Pooran, A., Lesosky , M. R., Esmail, A., Miller, M. G., Piercy, J., Michell, L., Dawson, R., Raine, R. I., Joubert, I., & Dheda, K. (2015). Burden of tuberculosis in intensive care units in Cape Town, South Africa, and assessment of the accuracy and effect on patient outcomes of the Xpert MTB/RIF test on tracheal aspirate samples for diagnosis of pulmonary tuberculosis: a prospective burden of disease study with a nested randomised controlled trial. Lancet Respiratory Medicine, 3, 621-30. doi:10.1016/S2213-2600(15)00198-8. Full text: http://dx.doi.org/10.1016/S2213-2600(15)00198-8

Mombaur, B., Lesosky , M. R., Liebenberg, L., Vreede, H., & Heckmann, J. M. (2015). Incidence of acetylcholine receptor-antibody-positive myasthenia gravis in South Africa. Muscle Nerve, 51, 533-7. doi:10.1002/mus.24348. Full text: http://dx.doi.org/10.1002/mus.24348

Peter, J., Theron, G., Chanda, D., Clowes, P., Rachow, A., Lesosky , M. R., Hoelscher, M., Mwaba, P., Pym, A., Dheda, K., & team, T. (2015). Test characteristics and potential impact of the urine LAM lateral flow assay in HIV-infected outpatients under investigation for TB and able to self-expectorate sputum for diagnostic testing. BMC Infectious Diseases, 15, 262. doi:10.1186/s12879-015-0967-z. Full text: http://dx.doi.org/10.1186/s12879-015-0967-z

Theron, G., Peter, J., Zijenah, L., Chanda, D., Mangu, C., Clowes, P., Rachow, A., Lesosky , M. R., Hoelscher, M., Pym, A., Mwaba, P., Mason, P., Naidoo, P., Pooran, A., Sohn, H., Pai, M., Stein, D. J., & Dheda, K. (2015). Psychological distress and its relationship with non-adherence to TB treatment: a multicentre study. BMC Infectious Diseases, 15, 253. doi:10.1186/s12879-015-0964-2. Full text: http://dx.doi.org/10.1186/s12879-015-0964-2

Abrahams, Z., Dave, J. A., Maartens, G., Lesosky , M. R., & Levitt, N. S. (2014). The development of simple anthropometric measures to diagnose antiretroviral therapy-associated lipodystrophy in resource limited settings. AIDS Research and Therapy, 11, 26. doi:10.1186/1742-6405-11-26. Full text: http://dx.doi.org/10.1186/1742-6405-11-26

De Andrade, R., Kotze, T., Lesosky , M. R., & Swanepoel, C. (2014). Comparison of myocardial perfusion during hemodialysis and hemodiafiltration. Nephron Clinical Practice, 126, 151-8. doi:10.1159/000360907. Full text: http://dx.doi.org/10.1159/000360907

Griffiths, B., Lesosky , M. R., & Ntsekhe, M. (2014). Self-reported use of evidence-based medicine and smoking cessation 6 - 9 months after acute coronary syndrome: a single-centre perspective. South African Medical Journal, 104, 483-7. doi:10.7196/samj.7798. Full text: http://dx.doi.org/10.7196/samj.7798

Kagina, B. M., Wiysonge, C. S., Lesosky , M. R., Madhi, S. A., & Hussey, G. D. (2014). Safety of licensed vaccines in HIV-infected persons: a systematic review protocol. Systematic Reviews Journal, 3, 101. doi:10.1186/2046-4053-3-101. Full text: http://dx.doi.org/10.1186/2046-4053-3-101

Kagina, B. M., Wiysonge, C. S., Lesosky, M., Madhi, S. A., & Hussey, G. D. (2014). Safety of licensed vaccines in HIV-infected persons : a systematic review protocol. Systematic reviews, 3(1), 1-6. doi:10.1186/2046-4053-3-101. Full text: http://dx.doi.org/10.1186/2046-4053-3-101

Marais, S., Wilkinson, K. A., Lesosky , M. R., Coussens, A. K., Deffur, A., Pepper, D. J., Schutz, C., Ismail, Z., Meintjes, G., & Wilkinson, R. J. (2014). Neutrophil-associated central nervous system inflammation in tuberculous meningitis immune reconstitution inflammatory syndrome. Clinical Infectious Diseases, 59, 1638-47. doi:10.1093/cid/ciu641. Full text: http://dx.doi.org/10.1093/cid/ciu641

Pietersen, E., Ignatius, E., Streicher, E. M., Mastrapa, B., Padanilam, X., Pooran, A., Badri, M., Lesosky , M. R., van Helden, P., Sirgel, F. A., Warren, R., & Dheda, K. (2014). Long-term outcomes of patients with extensively drug-resistant tuberculosis in South Africa: a cohort study. Lancet, 383, 1230-9. doi:10.1016/S0140-6736(13)62675-6. Full text: http://dx.doi.org/10.1016/S0140-6736(13)62675-6

Pietersen, E., Ignatius, E., Streicher, E. M., Mastrapa, B., Padanilam, X., Pooran, A., Badri, M., Lesosky, M., Town, C., & Africa, S. (2014). Long-term outcomes of patients with extensively drug-resistant tuberculosis in South Africa : a cohort study. Lancet, 6736(13), 1-10. doi:10.1016/S0140-6736(13)62675-6. Full text: http://dx.doi.org/10.1016/S0140-6736(13)62675-6

Theron, G., Zijenah, L., Chanda, D., Clowes, P., Rachow, A., Lesosky , M. R., Bara, W., Mungofa, S., Pai, M., Hoelscher, M., Dowdy, D., Pym, A., Mwaba, P., Mason, P., Peter, J., Dheda, K., & team, T. (2014). Feasibility, accuracy, and clinical effect of point-of-care Xpert MTB/RIF testing for tuberculosis in primary-care settings in Africa: a multicentre, randomised, controlled trial. Lancet, 383, 424-35. doi:10.1016/S0140-6736(13)62073-5. Full text: http://dx.doi.org/10.1016/S0140-6736(13)62073-5

Van Wyk, I. C., Goddard, A., de, C. B. B. M., Coetzer, J. A., Handel, I. G., Hanotte, O., Jennings, A., Lesosky , M. R., Kiara, H., Thumbi, S. M., Toye, P., Woolhouse, M. W., & Penzhorn, B. L. (2014). The impact of co-infections on the haematological profile of East African Short-horn Zebu calves. Parasitology, 141, 374-88. doi:10.1017/S0031182013001625. Full text: http://dx.doi.org/10.1017/S0031182013001625

Boyles, T. H., Whitelaw, A., Bamford, C., Moodley, M., Bonorchis, K., Morris, V., Rawoot, N., Naicker, V., Lusakiewicz, I., Black, J., Stead, D., Lesosky , M. R., Raubenheimer, P., Dlamini, S., & Mendelson, M. (2013). Antibiotic stewardship ward rounds and a dedicated prescription chart reduce antibiotic consumption and pharmacy costs without affecting inpatient mortality or re-admission rates. PLoS One, 8, e79747. doi:10.1371/journal.pone.0079747. Full text: http://dx.doi.org/10.1371/journal.pone.0079747

Lesosky , M. R., Dumas, S., Conradie, I., Handel, I. G., Jennings, A., Thumbi, S., Toye, P., & Bronsvoort, B. M. (2013). A live weight-heart girth relationship for accurate dosing of east African shorthorn zebu cattle. Trop Animal Health and Production, 45, 311-6. doi:10.1007/s11250-012-0220-3. Full text: http://dx.doi.org/10.1007/s11250-012-0220-3

Petzer, I. M., Karzis, J., Lesosky , M. R., Watermeyer, J. C., & Badenhorst, R. (2013). Host adapted intramammary infections in pregnant heifers which were co-housed and reared on fresh milk as calves. BMC Veterinary Research, 9, 49. doi:10.1186/1746-6148-9-49. Full text: http://dx.doi.org/10.1186/1746-6148-9-49

Lesosky , M. R., McGeer, A., Simor, A., Green, K., Low, D. E., & Raboud, J. (2011). Effect of patterns of transferring patients among healthcare institutions on rates of nosocomial methicillin-resistant Staphylococcus aureus transmission: a Monte Carlo simulation. Infection Control & Hospital Epidemiology, 32, 136-47. doi:10.1086/657945. Full text: http://dx.doi.org/10.1086/657945

Blackmore, K. M., Lesosky , M. R., Barnett, H., Raboud, J. M., Vieth, R., & Knight, J. A. (2008). Vitamin D from dietary intake and sunlight exposure and the risk of hormone-receptor-defined breast cancer. American Journal of Epidemiology, 168, 915-24. doi:10.1093/aje/kwn198. Full text: http://dx.doi.org/10.1093/aje/kwn198

Knight, J. A., Lesosky , M. R., Blackmore, K. M., Voigt, L. F., Holt, V. L., Bernstein, L., Marchbanks, P. A., Burkman, R. T., Daling, J. R., & Whittemore, A. S. (2008). Ovarian cysts and breast cancer: results from the Women's Contraceptive and Reproductive Experiences Study. Breast Cancer Research and Treatment, 109, 157-64. doi:10.1007/s10549-007-9634-4. Full text: http://dx.doi.org/10.1007/s10549-007-9634-4

Knight, J. A., Lesosky, Æ. M., Blackmore, Æ. K. M., Voigt, Æ. L. F., Holt, V. L., Bernstein, Æ. L., Marchbanks, Æ. P. A., Burkman, Æ. R. T., Daling, J. R., & Whittemore, Æ. A. S. (2008). Ovarian cysts and breast cancer: Results from the Women’s Contraceptive and Reproductive Experiences Study. Breast Cancer Research and Treatment, 109, 157-164. doi:10.1007/s10549-007-9634-4. Full text: http://dx.doi.org/10.1007/s10549-007-9634-4

Sahota, H., Barnett, H., Lesosky , M. R., Raboud, J. M., Vieth, R., & Knight, J. A. (2008). Association of vitamin D related information from a telephone interview with 25-hydroxyvitamin D. Cancer Epidemiology, Biomarkers & Prevention, 17, 232-8. doi:10.1158/1055-9965.EPI-07-0632. Full text: http://dx.doi.org/10.1158/1055-9965.EPI-07-0632

Wyk, I. C. V. A. N., Goddard, A., C, B. M. D. E., Coetzer, J. A. W., Handel, I. A. N. G., Hanotte, O., Jennings, A. M. Y., Lesosky, M., Kiara, H., Thumbi, S. A. M. M., Toye, P., Woolhouse, M. W., & Penzhorn, B. L. (2008). The impact of co-infections on the haematological profile of East African Short-horn Zebu calves. Parasitology, 141(2005), 374-388. doi:10.1017/S0031182013001625. Full text: http://dx.doi.org/10.1017/S0031182013001625

Knight, J. A., Lesosky, M., Barnett, H., Raboud, J. M., & Vieth, R. (2007). Vitamin D and Reduced Risk of Breast Cancer : A Population-Based Case-Control Study Vitamin D and Reduced Risk of Breast Cancer : A Population-Based Case-Control Study. Cancer Epidemiology, Biomarkers & Prevention, 16, 422-429. doi:10.1158/1055-9965.EPI-06-0865. Full text: http://dx.doi.org/10.1158/1055-9965.EPI-06-0865

Knight, J. A., Lesosky, M., Barnett, H., Raboud, J. M., & Vieth, R. (2007). Vitamin D and reduced risk of breast cancer: a population-based case-control study. Cancer Epidemiology, Biomarkers & Prevention, 16, 422-9. doi:10.1158/1055-9965.EPI-06-0865. Full text: http://dx.doi.org/10.1158/1055-9965.EPI-06-0865

Raboud, J., Lesosky, M., Sterling, S., Phillips, E., Walmsley, S., & Bayoumi, A. (2007). An estimate of the proportion of symptoms reported in self-administered questionnaires that are captured as adverse drug events in an observational database. HIV Clin Trials, 8, 311-9. doi:10.1310/hct0805-311. Full text: http://dx.doi.org/10.1310/hct0805-311

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