Director of Research Centre: Professor Mary-Ann Davies MBChB MMed Cape Town FCPHM SA
The Centre for Infectious Disease Epidemiology and Research (CIDER) conducts multi-disciplinary research on priority infectious diseases in Southern Africa, in order to improve disease prevention and management. The Centre has strong links to service providers at provincial and national level, and a long track record of conducting operations research around program effectiveness and service delivery challenges. Staff include epidemiologists, biostatisticians, mathematical modelers and public health specialists.
With HIV/Aids and tuberculosis contributing enormously to the disease burden in the Western Cape Province, a research grouping focussing on priority infectious diseases was formed in 2000 within the School of Public Health and Family Medicine. Since 2000, the Centre for Infectious Disease Epidemiology and Research (CIDER) has been involved in a wide range of interdisciplinary research and teaching spanning surveillance, HIV-prevention clinical trials, clinical epidemiology of tuberculosis and HIV therapy, socio-behavioural and health systems research. The Centre is comprised of a diverse group of staff, with strengths in epidemiology, biostatistics, mathematical modelling and medical anthropology.
The Centre works closely with provincial and national government.
Centre for Infectious Disease Epidemiology and Research
School of Public Health and Family Medicine
Faculty of Health Sciences
University of Cape Town
Tel: +27 21 406 6808
Fax:+27 21 406 6764
Current areas of research include:
CIDER staff are actively involved in policy processes and advisory groups, provincially, nationally and globally, including:
The African Health Information Exchange (AHIE) Project
In late 2016 CIDER was awarded a grant from the Bill and Melinda Gates Foundation to establish a reference African Health Information Exchange (AHIE). The aim was to deliver a replicable and context-appropriate implementation of a health information exchange for clinical data, working across national and provincial health departments in South Africa. An important outcome of this would be successful interoperability implementations for key systems that were critical to the HIV and TB response in South Africa. The AHIE project was undertaken by a consortium led by UCT CIDER. Consortium members were the National Department of Health (NDoH), the Council for Scientific and Industrial Research (CSIR), Jembi Health Systems, and the South African National Health Laboratory Service (NHLS). AHIE Video
The components of AHIE were:
HPRS: The scale up of the national health identifier and patient registration system, the Health Patient Registration System (HPRS) led by NDoH. Development of the HPRS was done by a team at the CSIR. HPRS Video
PHDC: The maturation of a set of technologies that could harmonize person-level health data and enable disease cascade reporting from diagnosis through to treatment success to assist patient management at all levels of the health system. The Western Cape Provincial Health Data Centre (PHDC) would serve as the innovation incubator for this component. PHDC Video
OpenHIM: The consolidation of a standards-based health information exchange (HIE) by adapting and maturing an open interoperability layer, the Open Health Information Mediator (OpenHIM), into a robust standards-based technology stack for widespread adoption. OpenHIM Video
SPV: The development of a viewing application for clinicians to access consolidated longitudinal clinical data, the single patient viewer (SPV). SPV Video
TIER.Net: The adaptation of TIER.Net to interoperate with other systems such as the HPRS and the NHLS laboratory information system. TIER.Net is an HIV and TB patient information system developed by CIDER and is used from facility level through to national level in about 4,000 facilities in South Africa. TIER Video
Exciting outcome of AHIE – The OpenIHP:
As software development work progressed throughout the AHIE project, it became clear that there was a need for an online solution to manage and monitor treatment of patients with HIV and TB. A dynamic data-driven forms engine was added to SPV that enabled the capture of new data to complement and be integrated with existing data in the PHDC, enabling users to view and capture on the same platform, reducing the need to import data from a separate, stand-alone system.
This new converged software platform is called the Open Integrated Health Platform (OpenIHP). Convergence to OpenIHP means that the PHDC, SPV, TIER.Net and enterprise reporting functionality can now be replicated and supported as one consolidated platform. In 2020 the effectiveness and adaptability of OpenIHP was successfully established and the platform has been playing an important role in the Western Cape Province’s response to COVID-19. OpenIHP Video
Mary-Ann Davies, Professor and Director
Phone: 021 406 6051
Mary-Ann Davies is a Public Health Medicine Specialist and Paediatric Clinical Epidemiologist at the University of Cape Town, where she is Director of the Centre for Infectious Disease Epidemiology and Research (CIDER). She convenes the MPH module on Infectious Disease Epidemiology. She is joint Principal Investigator of IeDEA Southern Africa, together with Matthias Egger from the University of Bern in Switzerland. Here major research interests are paediatric HIV treatment and prevention, especially HIV cohort research to address key policy and implementation questions.
Andrew Boulle, Professor
Phone: 021 406 6715
Andrew Boulle is a Public Health Medicine specialist with the Western Cape Provincial Department of Health and Professor of Public Health Medicine at the University of Cape Town. His research has predominantly addressed operational and clinical questions related to HIV service provision, often through analyses of HIV cohorts or population-based analyses. A further focus is context-appropriate information systems development in health care and the use and harmonisation of person-level health data for service and patient benefit. He currently provides oversight for the Provincial Health Data Centre in the Provincial Department of Health and leads the African Health Information Exchange consortium which brings together organisations working on interoperability and technical solutions in support of services for HIV and tuberculosis.
Landon Myer, Professor / Head of Department and Director of School
Phone: 021 406 6661
Landon Myer is Director and Head of the School of Public Health & Family Medicine at the University of Cape Town, South Africa. He has training in social anthropology, clinical medicine and epidemiology. His research focuses on women's, maternal and child health in the context of HIV. He has lead multiple clinical and health systems studies investigating the health of HIV-infected women receiving ART during pregnancy and postpartum, as well as the health and development of HIV-exposed and -infected children and adolescents.
Leigh Johnson, Associate Professor
Phone: 021 406 6981
Leigh Johnson is an epidemiologist and actuary, working at the Centre for Infectious Disease Epidemiology and Research (University of Cape Town). His research interests are in modelling of HIV and other infectious diseases, and most of his published work has focused on evaluating the impact of HIV prevention and treatment programmes in South Africa. He is the lead developer of the Thembisa model, a combined HIV and demographic model developed for South Africa (see www.thembisa.org). He is a member of the International Epidemiology Databases to Evaluate AIDS (IeDEA) collaboration and the UNAIDS Reference Group on Estimates, Modelling and Projections. He is also an editor of the journals AIDS and Infectious Disease Modelling.
Emma Kalk, Senior Clinical Research Officer
Phone: 021 406 6074
Dr Emma Kalk is a Clinical Epidemiologist in the Centre for Infectious Disease Epidemiology & Research where she manages projects linked to maternal and child health. She has a medical background in paediatric HIV clinical studies. The main focus of her current research has been the impact of HIV and ART in vertical transmission of HIV; this has expanded to include all pregnancy exposures with a special interest in pharmacovigilance during pregnancy and breast-feeding. Dr Kalk is also involved in projects designed to support a population-based database which links operational health data sources and sentinel site-based implementation science studies (most recently, this has included the Western Cape Pregnancy Exposure Registry). She collaborates nationally and within Africa.
Mpho Tlali, Clinical Research Officer
Phone: 021 650 4550
Morna Cornell, Senior Research Officer
Morna Cornell is Senior Research Officer at the Southern African IeDEA (International Epidemiology Databases to Evaluate AIDS) data centre based in the Centre for Infectious Disease Epidemiology (CIDER), School of Public Health & Family Medicine.
Morna has worked in HIV/AIDS since 1992, as Director of the AIDS Consortium, as a consultant for the Western Cape Department of Health, and subsequently as project manager of the CIPRA-SA (Comprehensive International Programme of Research on HIV/AIDS) programme.
Reshma Kassanjee, Senior Research Officer
Phone: 021 650 7194
Dr Reshma Kassanjee is a statistician at the Centre for Infectious Disease Epidemiology and Research (CIDER), and a member of the International Epidemiology Databases to Evaluate AIDS (IeDEA) collaboration. Reshma has a background in both mathematical statistics and computational and applied mathematics, and is most passionate about their contribution to public health and epidemiology. She spent a number of years developing methodologies and generating key results to support the estimation of HIV incidence. Her primary focus is infectious disease surveillance, and she aims both to provide answers to topical patient- and population-level questions, as well as to advance the required methodologies and tools, all with the goal of better informing decision making.
Ushma Mehta, Senior Research Officer
Phone: 021 650 1558
Carl Morrow, Senior Research Officer
Meg Osler, Senior Research Officer
Phone: 021 406 6717
Meg Osler is a Senior Technical Advisor for Strategic Information and stewards the development of the TIER.Net health information system being used in multiple countries in Africa. In addition, Meg continues her work as a PhD candidate considering the impact of policies on morbidity and mortality within the HIV services. Meg Osler's interests lie in improving health information ecosystems and using the resulting population-level data to improve patient management and service delivery.
Kim Anderson, Research Officer
Phone: 021 406 6602
Kim Anderson is a clinical epidemiologist at CIDER and a member of the International Epidemiology Databases to Evaluate AIDS (IeDEA) collaboration. She has a medical background in paediatic and adolescent HIV medicine. Her research areas of interest include health outcomes in perinatally-HIV-infected children and adolescents, morbidity in HIV-exposed uninfected children and prevention of mother-to-child transmission of HIV.
|Jonathan Euvrard||021 406 6636|
|Patience Nyakato||021 404 7737|
|Gem Patten||021 406 6482|
|Nontobeko Tena-Coki||021 650 2406|
|Nicola Maxwell||021 406 6602|
|Mariette Smith||021 406 6482|
|Meagan Bosland||021 406 6937|
|Robin Burley||021 406 6937|
|Gilles van Cutsem|
|Carmelita Sylvester||021 406 6808|
|Karin van Wyk||021 650 2316|
Reports and working papers
Reports and working papers